Science Buzz Lunch, May 25, 2013
Topics discussed included:
1)The novel technique "CLARITY" for producing "transparent" intact brain and other organs for visualizing macromolecular structures, as described in:
"Structural and molecular interrogation of intact biological systems"
by K. Chung et al.
in Nature Vol 497 16 May, 2013
2) The recently elucidated molecular basis of the sensation of itch. The neural signal of itch is transmitted by the neuropeptide Nppb: natriuretic polypeptide b
as reported in
"The Cells and Circuitry for Itch Responses in Mice"
by S. K. Mishra et al.
Science, 2013; 340 (6135)
This finding about Nppb resolves a long-standing controversy about whether itch is simply one manifestation of low-level pain: it isn't.
Topics discussed included:
1)The novel technique "CLARITY" for producing "transparent" intact brain and other organs for visualizing macromolecular structures, as described in:
"Structural and molecular interrogation of intact biological systems"
by K. Chung et al.
in Nature Vol 497 16 May, 2013
2) The recently elucidated molecular basis of the sensation of itch. The neural signal of itch is transmitted by the neuropeptide Nppb: natriuretic polypeptide b
as reported in
"The Cells and Circuitry for Itch Responses in Mice"
by S. K. Mishra et al.
Science, 2013; 340 (6135)
This finding about Nppb resolves a long-standing controversy about whether itch is simply one manifestation of low-level pain: it isn't.
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